Miami Florida is a vibrant city whose Cuban influence is reflected in the cafes and cigar shops that line Calle Ocho in Little Havana. Miami Beach, on barrier islands across the turquoise waters of Biscayne Bay, is home to glamorous South Beach, famed for its colorful art deco buildings, white sand, surfside hotels and trendsetting nightclubs.

Home to the Empire State Building, Times Square, Statue of Liberty and other iconic sites, New York City is a fast-paced, globally influential center of art, culture, fashion and finance. The city’s 5 boroughs sit where the Hudson River meets the Atlantic Ocean, with the island borough of Manhattan at the “Big Apple's" core.

Los Angeles is a sprawling Southern California city famed as the center of the nation’s film and television industry. Not far from its iconic Hollywood sign, studios such as Paramount Pictures, Universal and Warner Brothers offer behind-the-scenes tours. On Hollywood Boulevard, TCL Chinese Theater displays celebrities’ hand- and footprints, the Walk of Fame honors thousands of luminaries and vendors sell maps to stars’ homes.

Chicago, on Lake Michigan in Illinois, is among the largest cities in the U.S. Famed for its bold architecture, it has a skyline bristling with skyscrapers such as the iconic John Hancock Center, sleek, 1,451-ft. Willis Tower and neo-Gothic Tribune Tower. The city is also renowned for its museums, including the Art Institute and its expansive collections, including noted Impressionist works.